Quantification of trantinterol, its two metabolites and their primary conjugated metabolites in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study
Qin Feng
Yin Bincan
Wang Li-Juan
Li Kunjie
Li Famei
Xiong Zhili
· 2016
期刊名称：
Journal of Pharmaceutical and Biomedical Analysis
2016 年
117 卷
摘要：
A highly rapid, selective and sensitive ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was developed to simultaneously determine trantinterol, its major phase-I metabolites and their primary conjugated metabolites in human plasma. Waters Oasis HLB C18 solid phase extraction cartridges were used in the sample preparation. The separation was carried out on an ACQUITY UPLC??? BEH C
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