Nanocomposite Membranes Enhance Bone Regeneration Through Restoring Physiological Electric Microenvironment
Zhang Xuehui
Zhang Chenguang
Lin Yuanhua
Hu Penghao
Shen Yang
Wang Ke
Meng Song
Chai Yuan
Dai Xiaohan
Liu Xing
Liu Yun
Mo Xiaoju
Cao Cen
Li Shue
Deng Xuliang
Chen Lili
· 2016
期刊名称：
ACS Nano
2016 年
10 卷
8 期
摘要：
Physiological electric potential is well-known for its indispensable role in maintaining bone volume and quality. Although implanted biomaterials simulating structural, morphological, mechanical, and chemical properties of natural tissue or organ has been introduced in the field of bone regeneration, the concept of restoring physiological electric microenvironment remains ignored in biomaterials design. In this work, a flexible nanocomposite membrane mimicking the endogenous electric potential is fabricated to explore its bone defect repair efficiency. BaTiO
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