Helvetica Chimica Acta   2016 年 99 卷 3 期

2016.03.01

Seven new acyl glycosides, benzyl 5-O-vanilloyl-??-d-apiofuranosyl-(1??’6)-??-d-glucopyranoside (1), 4-hydroxy-3-methoxyphenyl 5-O-syringoyl-??-d-apiofuranosyl-(1??’6)-??-d-glucopyranoside (2), isopentyl 5-O-syringoyl-??-d-apiofuranosyl-(1??’6)-??-d-glucopyranoside (3), 3,4,5-trimethoxyphenyl 5-O-sinapoyl-??-d-apiofuranosyl-(1??’6)-??-d-glucopyranoside (4), 6-methoxy-7-[(6-O-sinapoyl-??-d-glucopyranosyl)oxy]coumarin (5), 6-methoxy-7-[(2-O-sinapoyl-??-d-glucopyranosyl)oxy]coumarin (6), and isopentyl ??-d-apiofuranosyl-(1??’6)-[5-O-syringoyl-??-d-apiofuranosyl-(1??’2)]-??-d-glucopyranoside (7), were isolated from Chinese folk herb Erycibe obtusifolia. Their structures were elucidated on the basis of extensive spectroscopic analysis, including UV, IR, MS, and 1D- and 2D-NMR techniques. Further, these compounds were evaluated against HCT-8 (human colon carcinoma), Bel-7402 (human liver carcinoma), BGC-823 (human stomach carcinoma), A549 (human lung carcinoma), and A2780 (human ovarian carcinoma) cell lines, however, none of them exhibited a significant bioactivity (IC