Carbachol improves the secretion of transplanted submandibular glands during the latent period after microvascular autologous transplantation for severe keratoconjunctivitis sicca

Liu Xiao-Jing Li M. Su Jia-Zeng Wang Zhen Xie Z. Yu Guang-Yan · 2016

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氨甲酰胆碱

期刊名称：

International Journal of Oral and Maxillofacial Surgery 2016 年 45 卷 10 期

发表日期：

2016.10.01

摘要：

Poor secretion of transplanted submandibular glands (SMGs) during the latent period may cause duct obstruction and affects the surgical outcome. The objective of this study was to investigate the efficacy and systemic side effects of carbachol on transplanted SMG secretion. Twenty-seven patients who underwent SMG transplantation for severe keratoconjunctivitis sicca were treated with subcutaneous injections of 0.2????mg/2????ml carbachol at 10 days, 1 month, and/or 3 months after surgery. The effect on secretion was evaluated by Schirmer test and technetium 99m (