Arsenic trioxide triggered calcium homeostasis imbalance and induced endoplasmic reticulum stress-mediated apoptosis in adult rat ventricular myocytes
Zhang Jingyi
Sun Guibo
Wang Min
Liao Ping
Du Yu-Yang
Yang Ke
Sun Xiaobo
· 2016
期刊名称：
Toxicology Research
2016 年
5 卷
2 期
摘要：
Arsenic trioxide (ATO) is a potent anticancer drug agent but its clinical use is often limited by severe cardiotoxicity. However, its exact mechanism remains poorly understood. In this study, we simultaneously explored the direct effect of ATO on cardiac contraction in adult rat ventricular myocytes and its effects on Ca
会员登录
