Two new dendrocandins with neurite outgrowth-promoting activity from Dendrobium officinale

Yang Liu Liu Shou-Jin Luo Huai-Rong Cui Juan Zhou Jun Wang Xuanjun Sheng Jun Hu Jiang-Miao · 2015

阅读量：227

联苄

期刊名称：

Journal of Asian Natural Products Research 2015 年 17 卷 2 期

发表日期：

2015.02.01

摘要：

Two new bibenzyl derivatives, dendrocandin T (1) and dendrocandin U (2), together with eight known bibenzyls, were isolated from the stems of Dendrobium officinale. Those compounds were sent for the first time for central nervous system-related bioassay and the results indicated that compounds 3, 4, and 5 have a certain degree of neurite outgrowth-promoting activity, and compounds 1, 2, 6, and 7 also have weak activity. The results indicated that D. officinale used as health food and traditional Chinese medicine "Tiepi Shihu" has a health function of neurotrophic effects.