Janus "nano-bullets" for magnetic targeting liver cancer chemotherapy
Shao Dan
Li Jing
Zheng Xiao
Pan Yue
Wang Zheng
Zhang Ming
Chen Qi-Xian
Dong Wen-Fei
Chen Li
· 2016
期刊名称:
Biomaterials
2016 年
100 卷
摘要:
Tumor-targeted delivery of anti-cancer drugs with controlled drug release function has been recognized as a promising strategy for pursuit of increased chemotherapeutic efficacy and reduced adverse effects. Development of magnetic nanoparticulates as delivery carriers to accommodate cytotoxic drugs for liver cancer treatment has evoked immense interest with respect to their convenience in biomedical application. Herein, we engineered multifunctional Janus nanocomposites, characterized by a head of magnetic Fe