Downregulation of β-adrenoceptors in isoproterenol-induced cardiac remodeling through HuR
Yin Qian
Yang Chengzhi
Wu Jimin
Lu Haiyan
Zheng Xiaohui
Zhang Youyi
Lv Zhizhen
Zheng Xiaopu
Li Zi J.
· 2016
期刊名称:
PLoS ONE
2016 年
11 卷
4 期
摘要:
??-adrenergic receptors (p-ARs) play an important role in cardiac remodeling, which is the key pathological process in various heart diseases and leads to heart failure. However, the regulation of p-AR expression in remodeling hearts is still unclear. This study aims to clarify the possible mechanisms underlying the regulation of ??