MRI-based estimation of liver function by intravoxel incoherent motion diffusion-weighted imaging

Zhang Jing Guo Yihao Tan Xiangliang Zheng Zeyu He Mengqi Xu Jun Mei Yingjie Zhang Jiajun Zhao Xixi Wang Chunhong Feng Yanqiu Chan Queenie Wu Yuankui Xu Yikai · 2016

阅读量：216

孩子–班丹尼·皮尤

DWI

语无伦次intravoxel的运动

肝功能

期刊名称：

Magnetic Resonance Imaging 2016 年 34 卷 8 期

发表日期：

2016.10.01

摘要：

Purpose To explore the usefulness of intravoxel incoherent motion (IVIM) to evaluate the hepatic functional reserve as expressed by the model for Child??“Pugh class. Materials and methods IVIM diffusion-weighted imaging (DWI) using 10 different b values were performed on a Philips 3.0??T MR scanner in 70 patients with liver cirrhosis and 60 healthy volunteers as the control group. Patients with liver cirrhosis were subdivided into three groups: Child??“Pugh class A: 29 cases; Child??“Pugh class B: 19 cases; Child??“Pugh class C: 22 cases. Pure molecular diffusion (D), pseudo-diffusion (D*), perfusion fraction (f) and apparent diffusion coefficient (ADC) values were calculated, and used to determine liver function, as indicated by the Child??“Pugh class. Results The ICC values of D, D*, f and ADC between two radiologists were 0.997, 0.986, 0.985 and 0.995, respectively. D*, f and ADC values of liver cirrhosis group were significantly lower than control group (P??