Expansion of myeloid-Derived suppressor cells in patients with acute coronary syndrome
Wang Yan-Ge
Xiong Xin
Chen Zhu-Yue
Liu Kan-Ling
Yang Jin-Hua
Wen Qiang
Wu Fang-Qin
Hu Xiao-Fan
Peng Yu-Dong
Wu Jing-Jing
Lian Yitian
Zhang Wen-Cai
Cheng Longxian
· 2015
期刊名称：
Cellular Physiology and Biochemistry
2015 年
35 卷
1 期
摘要：
Aim: The aim of this study was to explore whether the circulating frequency and function of myeloid-derived suppressor cells (MDSCs) are altered in patients with acute coronary syndrome (ACS). Methods: The frequency of MDSCs in peripheral blood was determined by flow cytometry, and mRNA expression in purified MDSCs was analyzed by real-time reverse transcription polymerase chain reaction (RT-PCR). The suppressive function of MDSCs isolated from different groups was also determined. The plasma levels of certain cytokines were determined using Bio-Plex Pro??? Human Cytokine Assays. Results: The frequency of circulating CD14
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