Illegitimate RAG-mediated recombination events are involved in IKZF1 Δ3–6 deletion in BCR-ABL1 lymphoblastic leukaemia
Dong Y.
Liu F.
Wu C.
Li S.
Zhao X.
Zhang P.
Jiao J.
Yu X.
Ji Y.
Zhang Mei
· 2016
期刊名称：
Clinical and Experimental Immunology
2016 年
185 卷
3 期
摘要：
Breakpoint cluster region-Abelson murine leukaemia viral oncogene homologue 1 (BCR??“ABL1), encoded by the Philadelphia (Ph) chromosome, is the characteristic of chronic myeloid leukaemia (CML) and a subset of acute lymphoblastic leukaemia (ALL). We demonstrated that expression of the Ik6 transcript, which lacked exons 3??“6, was observed exclusively in BCR??“ABL1
会员登录
