Denticulatains A and B: Unique stilbene-diterpene heterodimers from Macaranga denticulata
Yang Da-Song
Li Zi-Lei
Yan Hui
Yang Yong-Ping
Luo Huai-Rong
Xiao Wei-Lie
Li Xiaoli
· 2015
期刊名称:
RSC Advances
2015 年
5 卷
18 期
摘要:
Two novel heterodimers, denticulatains A (1) and B (2), were isolated from the fronds of Macaranga denticulata. They possess an unprecedented stilbene-diterpene-type skeleton, which represents a unique class of prenylated stilbene. Their structures were elucidated by comprehensive analyses of extensive NMR and MS spectroscopic data. Compounds 1 and 2 exhibited inhibitory activity against acetylcholinesterase with the inhibition ratios of 22.1% and 27.5%, respectively, at a concentration of 50 ??M. This journal is