Clinoposides A-F: Meroterpenoids with protective effects on H9c2 cardiomyocyte from: Clinopodium chinense
Zhu Yindi
Wu Haifeng
Ma Guo-Xu
Chen Rongchang
Long Hai-Lin
Zuo Zhi-Li
Luo Yun
Zhu Nai-Liang
Hou Bo
Xu Xu-Dong
Sun Guibo
Yang Jun-Shan
· 2016
期刊名称：
RSC Advances
2016 年
6 卷
9 期
摘要：
Six novel flavonoid-triterpene saponin meroterpenoids, clinoposides A-F (1-6), with two unusual skeletons were isolated from Clinopodium chinense. Clinoposides A-F represent a new class of isopentenyl flavonoid saponin. Their structures were determined based on spectroscopic data and chemical methods. The relative and absolute stereochemistries were assigned using a combination of NOESY and ECD. A possible biogenetic pathway for 1-6 is proposed. The protective effects of clinoposides A-F against H
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