Construction of negatively charged and environment-sensitive nanomedicine for tumor-targeted efficient siRNA delivery
Wang Yong
Xiao Hong
Fang Jing
Yu Xingsu
Su Zhenwei
Cheng Du
Shuai Xintao
· 2015
期刊名称：
Chemical Communications
2015 年
52 卷
6 期
摘要：
A novel siRNA delivery system based on a triblock copolymer with pH and reduction dual-sensitivity was introduced. The polyplex, having high delivery efficiency not dependent on surface charge reversion in response to the pH value of tumor tissue, was used for target gene silencing in cancer therapy.
会员登录
