Synthesis, anti-cancer evaluation of benzenesulfonamide derivatives as potent tubulin-targeting agents
Yang Jun
Yang Simin
Zhou Shanshan
Lu Dongbo
Ji Liyan
Li Zhongjun
Yu Siwang
Meng Xiangbao
· 2016
期刊名称：
European Journal of Medicinal Chemistry
2016 年
122 卷
摘要：
A series of benzenesulfonamide derivatives were synthesized and evaluated for their anti-proliferative activity and interaction with tubulin. These new derivatives showed significant activities against cellular proliferative and tubulin polymerization. Compound BA-3b proved to be the most potent compound with IC
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