Design of 5H-pyrrolo[2,3-b]pyrazine-2-phenyl Ether Derivatives as Potential JAK3 Inhibitor Based on Surflex Docking,3D-QSAR Modeling and Reverse Docking

刘蒙蒙王必武汪斌李静舒茂张娅林治华 · 2017

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JAK3 inhibitors

期刊名称：

结构化学 2017 年 12 期

摘要：

Tyrosine protein kinase JAK3 has a very important significance on organ transplantation and the treatment of autoimmune diseases, which has been a potential therapeutic target. In recent years, a large number of JAK3 inhibitors have been reported. Howe...