骨修复材料诱导的骨形成过程中细胞应激和稳态的表观遗传调控机制(英文)
会议名称:
中国生理学会基质生物学专业委员会第二次全国基质生物学学术会议
会议时间:
2017-06-07 00:00:01
摘要:
<正>Based on literatures and our previous study we hypothesize that the epigenetic mechanisms such as DNA methylation and miRNAs are involved in the regulation of bone formation during cellular stress response and homeostasis in the early phase of bone repair materials implantation.At the early stage of implantation of different materials in the porcine spinal fusion model and the chondrogenic differentiation of hBMSCs,we used gene chip