Salvianolic acid B protects against doxorubicin induced cardiac dysfunction: Via inhibition of ER stress mediated cardiomyocyte apoptosis

Chen Rongchang Sun Guibo Sun Xiaobo · 2016

阅读量：62

期刊名称：

Toxicology Research 2016 年 5 卷 5 期

发表日期：

2016

摘要：

Salvia miltiorrhiza Bunge is a well-known medicinal plant in China. Salvianolic acid B (Sal B) is the most abundant bioactive compound extracted from the root of S. miltiorrhiza. The present study investigates the effect of Sal B on cardiac function and cardiomyocyte apoptosis in doxorubicin (DOX)-treated mice. After pretreatment with Sal B (2 mg kg