DNA methylation in cystathionine-γ-lyase (CSE) gene promoter induced by ox-LDL in macrophages and in apoE knockout mice
Du Hua-Ping
Li Jiaojiao
You Shou-Jiang
Wang Yali
Wang Fen
Cao Yong-Jun
Hu Li-Fang
Liu Chun-Feng
· 2016
期刊名称：
Biochemical and Biophysical Research Communications
2016 年
469 卷
3 期
摘要：
Recent studies suggest that epigenetic alterations such as DNA methylation control many aspects of monocytes/macrophages and participate in the pathogenesis of atherosclerosis, a lipid-driven inflammatory disorder. Our and other groups demonstrated that dysregulation of cystathionine ??-lyase (CSE) -hydrogen sulfide (H
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