Expression and immunogenic characterization of recombinant gp350 for developing a subunit vaccine against Epstein-Barr virus
Wang Man
Jiang Shuai
Han Zhenwei
Zhao Bing
Wang Li’ao
Zhou Zhixia
Wang Yefu
· 2016
期刊名称:
Applied Microbiology and Biotechnology
2016 年
100 卷
3 期
摘要:
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is linked to the development of various malignancies. There is an urgent need for effective vaccines against EBV. EBV envelope glycoprotein gp350 is an attractive candidate for a prophylactic vaccine. This study was undertaken to produce the truncated (codons 1-443) gp350 protein (gp350